Description

4-Oxo-4-[2-(Trimethylazaniumyl)Ethoxy]Butanoate Hydroiodide is a specialized quaternary ammonium salt derivative of succinic acid, serving as a high-purity synthetic intermediate and building block. Its molecular structure, featuring a charged trimethylammonium moiety linked via an ethoxy spacer to a butanoate ester, makes it valuable for introducing cationic functionality into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise molecular modification and controlled reactivity.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring cationic or betaine-like structures for enhanced bioavailability or specific receptor interactions.
• Bioconjugation & Prodrug Synthesis: Acts as a linker or functionalizing agent for attaching drug molecules to carriers, antibodies, or polymers to create targeted therapies or improve solubility.
• Agrochemical Research: Employed in developing novel herbicides, fungicides, or plant growth regulators where the quaternary ammonium group can influence systemic activity or environmental stability.
• Surface-Active Agent Precursor: Serves as a key intermediate for synthesizing specialized cationic surfactants or fabric softeners with unique ester linkages.
• Polymer Modification: Used to introduce permanent positive charges into polymer backbones for creating anion-exchange resins, conductive materials, or antimicrobial coatings.
• Biochemical Research: Applied in enzymology and molecular biology studies as a substrate analog or inhibitor for enzymes interacting with carboxylic esters or charged substrates.

Basic Information

Item	Detail
Product Name	4-Oxo-4-[2-(Trimethylazaniumyl)Ethoxy]Butanoate Hydroiodide
CAS No.	14720-92-4
Molecular Formula	C9H18INO4
Molecular Weight	331.15 g/mol
Synonyms	2-[(Carboxycarbonyl)oxy]-N,N,N-trimethylethanaminium Iodide; Succinic Acid Mono(2-trimethylammonioethyl) Ester Iodide; (2-Trimethylammonioethyl) Hydrogen Succinate Iodide; TMES Iodide; 4-Oxo-4-(2-trimethylammonioethoxy)butanoic Acid Hydroiodide; Butanoic Acid, 4-oxo-4-[2-(trimethylazaniumyl)ethoxy]-, Iodide
EINECS	Contact for details

Quality Control

Our 4-Oxo-4-[2-(Trimethylazaniumyl)Ethoxy]Butanoate Hydroiodide is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, impurity profile, and residual solvents. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions, ideally with desiccant, to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.