Description

2-Chloro-2-Deoxy-D-Glucose is a halogenated glucose analog that serves as a crucial biochemical tool and synthetic intermediate. This compound is valued for its ability to interfere with cellular glycosylation processes, making it a key reagent in metabolic and glycobiology research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic agents and conducting fundamental biochemical studies.

Application

• Biochemical Research: Used as a metabolic inhibitor to study glucose metabolism, glycosylation pathways, and cellular energy regulation.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex glycosidase inhibitors or antiviral/antitumor drug candidates.
• Antiviral Research: Investigated for its potential to inhibit the replication of certain viruses that rely on host cell glycosylation machinery.
• Standards & Reference Material: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Institutional Research: A fundamental reagent for universities and research institutes exploring carbohydrate chemistry and cell biology.

Basic Information

Product Name	2-Chloro-2-Deoxy-D-Glucose
CAS No.	14685-79-1
Molecular Formula	C6H11ClO5
Molecular Weight	198.60 g/mol
Synonyms	2-Chloro-2-deoxy-D-glucose; 2-Chloro-2-deoxyglucose; 2-Deoxy-2-chloro-D-glucose; 2-Chloro-2-deoxy-D-glucopyranose; Chlorodeoxyglucose; 2-CDG; 2-Cl-2-dGlc
EINECS	Contact for details

Quality Control

Our 2-Chloro-2-Deoxy-D-Glucose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and specific tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.