Description

tert-Butoxycarbonylamino-Naphthalen-1-Yl-Acetic Acid is a high-purity, protected amino acid derivative featuring a naphthalene moiety. This compound serves as a critical building block (synthon) in advanced organic synthesis, particularly for the construction of complex molecules. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers engaged in peptide mimetics, drug discovery, and material science projects.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Chemistry: Used to incorporate naphthalene-based, non-natural amino acids into peptide chains to enhance stability, bioavailability, or binding affinity.
• Organic Synthesis Building Block: Serves as a versatile synthon for constructing complex organic architectures in medicinal and process chemistry.
• Bioconjugation & Labeling: Potential use in creating fluorescent probes or affinity tags due to the aromatic naphthalene system.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials.
• Academic & Industrial R&D: Essential reagent for research laboratories focusing on synthetic methodology and new chemical entity development.

Basic Information

Product Name	tert-Butoxycarbonylamino-Naphthalen-1-Yl-Acetic Acid
CAS No.	14675-99-1
Molecular Formula	C₁₇H₁₉NO₄
Molecular Weight	301.34 g/mol
Synonyms	Boc-1-Nal-OH; (1-Naphthyl)-N-Boc-glycine; N-(tert-Butoxycarbonyl)-1-naphthylglycine; 2-[(tert-Butoxycarbonyl)amino]-2-(1-naphthyl)acetic acid; N-Boc-1-naphthylglycine; Nα-Boc-1-naphthylglycine; Boc-Nap-OH; 2-((tert-Butoxycarbonyl)amino)-2-(naphthalen-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our tert-Butoxycarbonylamino-Naphthalen-1-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maintain long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.