Description

5-Nitro-3H-1,2-benzoxathiole 2,2-dioxide is a specialized heterocyclic compound featuring a benzoxathiole core structure functionalized with a nitro group and a sulfone moiety. This unique molecular architecture makes it a valuable high-purity intermediate for advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring the benzoxathiole or sulfone pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced organic materials.
• Dye and Pigment Synthesis: Employed in the production of high-performance dyes and organic pigments due to the presence of the nitro and sulfone groups.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme mechanisms or as a tagged molecule in biochemical assays.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing specific functional groups or constructing complex ring systems in multi-step syntheses.

Basic Information

Item	Detail
Product Name	5-Nitro-3H-1,2-benzoxathiole 2,2-dioxide
CAS No.	14618-10-1
Molecular Formula	C7H5NO5S
Molecular Weight	215.18 g/mol
Synonyms	5-Nitro-1,2-benzoxathiol-3-one 2,2-dioxide; 5-Nitro-3H-1,2-benzoxathiole-3-one 2,2-dioxide; 5-Nitro-3-oxo-1,2-benzoxathiole 2,2-dioxide; 5-Nitro-3-hydroxy-1,2-benzisothiazole 1,1-dioxide; 5-Nitro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide; 5-Nitro-3-hydroxybenzo[d]isothiazole 1,1-dioxide; 5-Nitro-3-oxo-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide
EINECS	Contact for details

Quality Control

Our 5-Nitro-3H-1,2-benzoxathiole 2,2-dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.