Description

5H-Pyrano[4,3-B]Pyridin-5-One,7,8-Dihydro-7-Phenyl-,Hydrochloride(8Ci) is a heterocyclic organic compound that serves as a crucial advanced intermediate in modern pharmaceutical synthesis. Its unique fused pyrano-pyridine core structure makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This high-purity intermediate is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex molecule production.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Organic Synthesis Building Block: Used in constructing complex heterocyclic frameworks for medicinal chemistry and material science applications.
• Research & Development (R&D): Essential for academic and industrial laboratories exploring novel chemical pathways and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in multi-step synthesis processes for producing final drug substances under Good Manufacturing Practice (GMP) conditions.
• Process Chemistry: Utilized in scale-up and optimization studies for efficient and cost-effective manufacturing routes.

Basic Information

Product Name	5H-Pyrano[4,3-B]Pyridin-5-One,7,8-Dihydro-7-Phenyl-,Hydrochloride(8Ci)
CAS No.	14578-17-7
Molecular Formula	C₁₄H₁₂ClNO₂
Molecular Weight	261.70 g/mol
Synonyms	7,8-Dihydro-7-phenyl-5H-pyrano[4,3-b]pyridin-5-one hydrochloride; 7-Phenyl-7,8-dihydro-5H-pyrano[4,3-b]pyridin-5-one hydrochloride; 5H-Pyrano[4,3-b]pyridin-5-one, 7,8-dihydro-7-phenyl-, hydrochloride; 14578-17-7; 7-Phenyl-5H,7H,8H-pyrano[4,3-b]pyridin-5-one hydrochloride
EINECS	Contact for details

Quality Control

Our production of 5H-Pyrano[4,3-B]Pyridin-5-One,7,8-Dihydro-7-Phenyl-,Hydrochloride(8Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and manufacturing processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to support customer needs for regulatory filings and GMP-grade applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed under dry, inert conditions to prevent moisture absorption. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.