Description

(1S,2S)-2-Phenylcyclopropanecarbohydrazide is a high-purity, chiral cyclopropane derivative that serves as a critical synthetic intermediate. Its value lies in its rigid, three-membered ring structure and functional hydrazide group, enabling precise stereochemical control in complex organic syntheses. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its specific stereochemistry is essential for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the cyclopropane moiety contributes to biological efficacy.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in enantioselective catalysis.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex, stereodefined molecular architectures.
• Chemical Probe Development: Utilized in medicinal chemistry for creating tool compounds to study biological pathways and protein interactions.

Basic Information

Product Name	(1S,2S)-2-Phenylcyclopropanecarbohydrazide
CAS No.	14561-40-1
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	(1S,2S)-2-Phenylcyclopropanecarboxylic acid hydrazide; (1S-cis)-2-Phenylcyclopropanecarbohydrazide; trans-2-Phenylcyclopropanecarbohydrazide; (1S,2S)-rel-2-Phenylcyclopropanecarbohydrazide; 2-Phenylcyclopropanecarbohydrazide, (1S,2S)-; Cyclopropanecarbohydrazide, 2-phenyl-, (1S,2S)-; (1S,2S)-2-Phenylcyclopropane-1-carbohydrazide
EINECS	Contact for details

Quality Control

Our (1S,2S)-2-Phenylcyclopropanecarbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.