Description

3',5'-Dichloroacetophenone is a versatile chlorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its value lies in its reactive carbonyl and halogen groups, which enable precise chemical transformations for creating complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a dichlorophenyl moiety.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the dichloroacetophenone structure serves as a core scaffold.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for Friedel-Crafts acylation, nucleophilic substitution, and reduction reactions.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other specialty chemicals requiring specific chlorinated aromatic structures.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for metal catalysis and asymmetric synthesis.

Basic Information

Product Name	3',5'-Dichloroacetophenone
CAS No.	14401-72-0
Molecular Formula	C8H6Cl2O
Molecular Weight	189.04 g/mol
Synonyms	1-(3,5-Dichlorophenyl)ethanone; 3,5-Dichloroacetophenone; 3,5-Dichlorophenyl methyl ketone; m,m'-Dichloroacetophenone; Ethanone, 1-(3,5-dichlorophenyl)-; NSC 406079
EINECS	Contact for details

Quality Control

Our 3',5'-Dichloroacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical parameters is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.