Description

Benzocyclobutyl-1-Carboxylic Acid is a versatile and synthetically valuable organic compound featuring a strained four-membered cyclobutane ring fused to a benzene ring. This unique structure makes it a crucial high-purity building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring strained ring systems for biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Employed as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties.
• Academic and Industrial R&D: A fundamental reagent for methodological studies in organic chemistry, including ring-opening and cross-coupling reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance, flavor, and electronic chemical intermediates.

Basic Information

Product Name	Benzocyclobutyl-1-Carboxylic Acid
CAS No.	14381-41-0
Molecular Formula	C9H8O2
Molecular Weight	148.16 g/mol
Synonyms	1-Benzocyclobutanecarboxylic Acid; BCB-COOH; Bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic Acid; Benzocyclobutane-1-carboxylic Acid; 1-Carboxybenzocyclobutane
EINECS	Contact for details

Quality Control

Our Benzocyclobutyl-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity research and cGMP-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.