Description

n-Octadecanoyl-D-Valine is a high-purity, chiral amino acid derivative where the amino group of D-valine is acylated with stearic acid. This compound matters as a critical building block in advanced pharmaceutical synthesis and peptide research, offering precise stereochemical control. It is needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic peptides and chiral intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce lipophilic character.
• Bioconjugation: Serves as a linker or modifier for coupling peptides to other molecules, lipids, or surfaces in drug delivery systems.
• Biochemical Research: Employed in studying enzyme-substrate interactions, membrane protein behavior, and as a standard in analytical method development.
• Cosmetic Peptides: Potential ingredient in the synthesis of bioactive peptides for advanced skincare formulations.
• Asymmetric Catalysis: Can be utilized as a chiral auxiliary or ligand in asymmetric synthetic transformations.

Basic Information

Product Name	n-Octadecanoyl-D-Valine
CAS No.	14379-33-0
Molecular Formula	C₂₃H₄₅NO₃
Molecular Weight	383.61 g/mol
Synonyms	Stearoyl-D-valine; D-Valine, N-stearoyl-; N-Octadecanoyl-D-valine; N-Stearoyl-D-valine; (R)-2-(Octadecanamido)-3-methylbutanoic acid; (R)-2-Stearamido-3-methylbutanoic acid; LSN3290758; CTK8G7242
EINECS	Contact for details

Quality Control

Our n-Octadecanoyl-D-Valine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including chiral purity verification, assay, and impurity profiling to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.