Description

(-)-7-Ethyl-1,4,5,6,7,8,9,10-Octahydro-11-Methoxy-2H-3,7-Methanoazacycloundecino[5,4-B]Indole is a complex, chiral indole alkaloid derivative with a unique bridged polycyclic structure. This compound is of significant interest in advanced organic synthesis and pharmaceutical research, particularly as a sophisticated building block or a potential pharmacophore. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries. The specific stereochemistry and functional groups present make it a valuable intermediate for exploring novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct intricate nitrogen-containing heterocycles due to its rigid, three-dimensional structure.
• Medicinal Chemistry Research: Employed as a reference standard or a starting material in structure-activity relationship (SAR) studies to optimize drug candidate properties.
• Agrochemical Research: Investigated as a potential intermediate for developing novel, high-specificity pesticides or herbicides.
• Biochemical Tool Compound: May be used in biochemical assays to study enzyme interactions or receptor binding mechanisms related to indole alkaloid pathways.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in synthetic methodology and alkaloid chemistry.

Basic Information

Product Name	(-)-7-Ethyl-1,4,5,6,7,8,9,10-Octahydro-11-Methoxy-2H-3,7-Methanoazacycloundecino[5,4-B]Indole
CAS No.	14358-58-8
Molecular Formula	C21H28N2O
Molecular Weight	324.46 g/mol
Synonyms	(-)-Yohimbane derivative; 11-Methoxy-yohimbane; 3,7-Methanoazacycloundecino[5,4-b]indole derivative; 7-Ethyl-1,4,5,6,7,8,9,10-octahydro-11-methoxy-2H-3,7-methanoazacycloundecino[5,4-b]indole; (7S)-7-Ethyl-1,2,3,4,5,6,7,8,9,10-decahydro-11-methoxy-3,7-methanoazacycloundecino[5,4-b]indole; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (-)-7-Ethyl-1,4,5,6,7,8,9,10-Octahydro-11-Methoxy-2H-3,7-Methanoazacycloundecino[5,4-B]Indole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request. We support research and development with reliable, high-quality materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.