Description

(R)-4-Benzyloxymethyl-2,2-Dimethyl-1,3-Dioxolane is a high-value chiral building block and protected intermediate widely used in asymmetric synthesis. This compound is critical for the efficient and stereoselective construction of complex molecules, particularly in pharmaceutical development. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the production of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for the synthesis of enantiomerically pure drugs, particularly those requiring specific stereochemistry for biological activity.
• Asymmetric Catalysis & Ligand Synthesis: Used in the preparation of chiral ligands and catalysts for enantioselective transformations.
• Natural Product Synthesis: Serves as a protected glycerol or glyceraldehyde equivalent in the total synthesis of complex natural products.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific isomer activity is required.
• Advanced Material Precursors: Can be utilized in the synthesis of specialized monomers or polymers with controlled stereochemistry.

Basic Information

Item	Details
Product Name	(R)-4-Benzyloxymethyl-2,2-Dimethyl-1,3-Dioxolane
CAS No.	14347-83-2
Molecular Formula	C13H18O3
Molecular Weight	222.28 g/mol
Synonyms	(R)-(-)-4-(Benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane; (R)-2,2-Dimethyl-4-(benzyloxymethyl)-1,3-dioxolane; (R)-4-(Benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane; (R)-1,2-Isopropylidene-4-O-benzyl-D-threitol; (R)-1,2-O-Isopropylidene-4-O-benzyl-D-threitol; (R)-1,2-O-Isopropylidene-4-O-benzyl-D-threitol; (R)-D-1,2-O-Isopropylidene-4-O-benzylthreitol; D-1,2-O-Isopropylidene-4-O-benzylthreitol (R)-
EINECS	Contact for details

Quality Control

Our (R)-4-Benzyloxymethyl-2,2-Dimethyl-1,3-Dioxolane is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including HPLC, chiral GC, and NMR, to verify identity, purity, and optical rotation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0% ee
Specific Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.