Description

Boc-Gly-Pro-Oh is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing therapeutic peptides, biochemical probes, and novel materials.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of therapeutic peptide APIs and drug candidates.
• Biochemical Research: Used in academic and industrial R&D for studying enzyme substrates, inhibitors, and protein-protein interactions.
• Peptide Library Construction: Essential component for generating combinatorial peptide libraries for screening and discovery.
• Custom Peptide Synthesis: Serves as a critical starting material for CROs and CDMOs offering bespoke peptide manufacturing services.
• Protease Substrate Analogues: Employed in the development of specific substrates or inhibitors for proteolytic enzymes.
• Material Science: Potential use in creating peptide-based biomaterials and hydrogels.

Basic Information

Product Name	Boc-Gly-Pro-Oh
CAS No.	14296-92-5
Molecular Formula	C₁₂H₂₀N₂O₅
Molecular Weight	272.30 g/mol
Synonyms	Boc-Gly-Pro-OH; Boc-Glycyl-L-proline; (2S)-1-[(2-{[(2-Methylpropan-2-yl)oxy]carbonyl}amino)acetyl]pyrrolidine-2-carboxylic acid; tert-Butyloxycarbonyl-glycyl-proline; N-(tert-Butoxycarbonyl)glycyl-L-proline; Boc-Gly-Pro; BOC-Gly-Pro; N-Boc-glycyl-L-proline
EINECS	Contact for details

Quality Control

Our Boc-Gly-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance and supply chain reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-70° to -80° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.