Description

(1R,2R)-(-)-n-Methylpseudoephedrine is a chiral organic compound belonging to the class of substituted amphetamines, serving as a key intermediate and building block in sophisticated organic synthesis. Its primary commercial value lies in its stereochemical purity, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and advanced material sectors that require high-purity chiral precursors.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Asymmetric Synthesis Catalyst/Chiral Auxiliary: Utilized in stereoselective reactions to induce chirality in target molecules, enabling the production of single-enantiomer compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and regulatory laboratories.
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and the development of novel therapeutic agents.
• Agrochemical Synthesis: Acts as a building block for creating enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: Employed in chemical research focused on developing new synthetic methodologies and exploring novel chiral compounds.

Basic Information

Product Name	(1R,2R)-(-)-n-Methylpseudoephedrine
CAS No.	14222-20-9
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	(1R,2R)-(-)-N-Methylephedrine; (1R,2R)-(-)-N-Methylpseudoephedrine; (-)-N-Methylpseudoephedrine; (1R,2R)-2-(Methylamino)-1-phenylpropan-1-ol; d-N-Methylpseudoephedrine; (1R,2R)-N-Methyl-ψ-ephedrine; N-Methylephedrine (pseudo- isomer)
EINECS	Contact for details

Quality Control

Our (1R,2R)-(-)-n-Methylpseudoephedrine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.