Description

5-Nitro-3-Phenyl-1H-Indole-2-Carboxylic Acid is a high-purity, synthetically valuable indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both nitro and carboxylic acid functional groups on the indole core, makes it an essential intermediate for developing novel pharmaceuticals and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Material Science: Serves as a monomer or functional component in the creation of specialty polymers, dyes, and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	5-Nitro-3-Phenyl-1H-Indole-2-Carboxylic Acid
CAS No.	14182-37-7
Molecular Formula	C15H10N2O4
Molecular Weight	282.25 g/mol
Synonyms	5-Nitro-3-phenyl-1H-indole-2-carboxylic acid; 2-Carboxy-5-nitro-3-phenylindole; 3-Phenyl-5-nitroindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 5-nitro-3-phenyl-; 5-Nitro-3-phenylindole-2-carboxylic acid; NSC 163082; AI3-52090
EINECS	Contact for details

Quality Control

Our 5-Nitro-3-Phenyl-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades, including pharmaceutical intermediates grade, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.