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Bis(4-Methoxyphenyl)Phenylphosphine CAS NO 14180-51-9


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CAS No.:14180-51-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bis(4-Methoxyphenyl)Phenylphosphine is a specialized organophosphorus compound featuring a central phosphorus atom bonded to phenyl and two methoxyphenyl groups. This structure makes it a valuable ligand and intermediate in advanced chemical synthesis, particularly in catalytic processes where electron-donating methoxy groups can fine-tune reactivity. It is primarily sought after by research institutions and industrial R&D departments engaged in developing novel catalysts, pharmaceuticals, and high-performance materials.

Application

  • Catalyst Ligand in Cross-Coupling Reactions: Serves as a key phosphine ligand in palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings for constructing complex organic molecules.
  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds requiring specific phosphine-based architectures.
  • Material Science Research: Acts as a precursor or building block in the development of novel polymers, ligands for metal-organic frameworks (MOFs), and other functional materials.
  • Organic Synthesis Reagent: Employed as a nucleophilic phosphine reagent in various organic transformations, including Mitsunobu reactions and reductions.
  • Agrochemical Synthesis: Utilized in the research and development of new crop protection agents and plant growth regulators.
  • Coordination Chemistry: Functions as a chelating or monodentate ligand for transition metals, forming complexes studied for their catalytic and photophysical properties.

Basic Information

Product Name Bis(4-Methoxyphenyl)Phenylphosphine
CAS No. 14180-51-9
Molecular Formula C20H19O2P
Molecular Weight 322.34 g/mol
Synonyms Phenylbis(4-methoxyphenyl)phosphine; (4-Methoxyphenyl)phenylphosphine; Bis(p-anisyl)phenylphosphine; Phosphine, phenylbis(4-methoxyphenyl)-; P,P-Bis(4-methoxyphenyl)phenylphosphine; Trisubstituted Phosphine Ligand; 14180-51-9 (CAS)
EINECS Contact for details

Quality Control

Our Bis(4-Methoxyphenyl)Phenylphosphine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to verify identity and assay. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). Due to its sensitivity to oxidation, minimize exposure to air during handling.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Melting Point Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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