Description

4-Iodo-Dl-Phenylalanine is a halogenated derivative of the essential amino acid phenylalanine, where an iodine atom is introduced at the para position of the aromatic ring. This structural modification makes it a valuable non-natural amino acid and a versatile synthetic intermediate in advanced organic and medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel compounds, including peptide-based therapeutics, radiopharmaceuticals, and molecular probes.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in oncology and neurology research.
• Peptide Synthesis: Used to incorporate iodine-labeled amino acids into peptides for structure-activity relationship (SAR) studies and bio-conjugation.
• Radiopharmaceutical Precursor: Serves as a precursor for iodine-123 or iodine-131 labeled compounds used in diagnostic imaging and targeted radiotherapy.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Organic Synthesis: Acts as a versatile intermediate for cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex aromatic systems.
• Material Science: Potential monomer for synthesizing specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	4-Iodo-Dl-Phenylalanine
CAS No.	14173-41-2
Molecular Formula	C9H10INO2
Molecular Weight	291.09 g/mol
Synonyms	DL-4-Iodophenylalanine; (±)-4-Iodo-DL-phenylalanine; p-Iodo-DL-phenylalanine; 4-Iodo-DL-α-aminohydrocinnamic acid; (RS)-2-Amino-3-(4-iodophenyl)propanoic acid; 4-I-Phe; Iodo phenylalanine
EINECS	Contact for details

Quality Control

Our 4-Iodo-Dl-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.