Description

(+/-)-trans-1,2-Cyclohexanedicarboxylic Anhydride CAS NO 14166-21-3 is a versatile, high-purity cyclic anhydride used as a key building block in advanced organic synthesis. This compound is valued for its reactivity as an electrophile, enabling the formation of esters, amides, and imides under mild conditions. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, polymer, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for creating cyclic imide structures.
• Epoxy Resin Curing Agent: Acts as a hardener/anhydride curing agent for epoxy resins, imparting improved thermal stability and mechanical properties to coatings and composites.
• Polymer Modification: Used in the production of alkyd resins, polyesters, and plasticizers to modify flexibility, durability, and chemical resistance.
• Organic Synthesis Reagent: A versatile reagent for Diels-Alder reactions, ring-opening polymerizations, and the preparation of chiral auxiliaries and ligands.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of monomers for advanced electronic and optoelectronic materials.
• Corrosion Inhibitor Precursor: Used in formulating additives for coatings and lubricants that protect metal surfaces.

Basic Information

Product Name	(+/-)-trans-1,2-Cyclohexanedicarboxylic Anhydride
CAS No.	14166-21-3
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	trans-1,2-Cyclohexanedicarboxylic Anhydride; Hexahydrophthalic Anhydride (HHPA) (mixed isomers); 1,2-Cyclohexanedicarboxylic Acid Anhydride; Cyclohexane-1,2-dicarboxylic Anhydride; 4-Cyclohexene-1,2-dicarboxylic Anhydride, hexahydro-; NSC 8652; trans-Hexahydrophthalic Anhydride
EINECS	238-009-9

Quality Control

Our (+/-)-trans-1,2-Cyclohexanedicarboxylic Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay, identification, and impurity profiling, to ensure it meets precise specifications. A Certificate of Analysis (COA) detailing purity, physical properties, and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent hydrolysis and degradation upon prolonged exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	32 - 36 °C
Water Content (KF)	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.