Description

4,6-o-Benzylidene-D-Glucal is a protected carbohydrate derivative, specifically a benzylidene acetal of D-glucal, serving as a crucial chiral building block in synthetic organic chemistry. Its value lies in its role as a versatile intermediate for the stereoselective synthesis of complex glycosides, C-glycosides, and other biologically active molecules. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly those developing novel therapeutics, diagnostics, and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of novel antiviral, anticancer, and antibiotic agents.
• Glycochemistry Research: Fundamental building block for synthesizing complex oligosaccharides, glycoconjugates, and glycomimetics.
• C-Glycoside Synthesis: Precursor for creating stable C-glycosidic linkages found in various natural products and drug candidates.
• Agrochemical Development: Intermediate in the synthesis of advanced, bioactive carbohydrate-based crop protection agents.
• Catalyst & Ligand Preparation: Used to develop chiral ligands and organocatalysts for asymmetric synthesis.
• Diagnostic Reagent Manufacturing: Component in the synthesis of labeled sugars and probes for biochemical assays.

Basic Information

Product Name	4,6-o-Benzylidene-D-Glucal
CAS No.	14125-70-3
Molecular Formula	C₁₃H₁₄O₅
Molecular Weight	250.25 g/mol
Synonyms	4,6-O-Benzylidene-D-glucal; 4,6-O-(Phenylmethylene)-D-glucal; D-Glucal, 4,6-O-benzylidene-; 1,5-Anhydro-4,6-O-benzylidene-2-deoxy-D-arabino-hex-1-enitol; 2,3-Dideoxy-4,6-O-benzylidene-D-erythro-hex-2-enopyranose; Benzylidene-D-glucal
EINECS	Contact for details

Quality Control

Our 4,6-o-Benzylidene-D-Glucal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure high chemical purity and chiral integrity. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your project's exact requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.