Description

Calcium46 CAS NO 13981-77-6 is a stable, non-radioactive isotope of calcium, specifically the isotope with mass number 46. This high-purity isotopic material is critical for advanced scientific research and industrial applications where precise tracking and quantification of calcium are required. It is an essential reagent for isotope dilution mass spectrometry (IDMS), metabolic pathway studies, and the development of high-precision calibration standards. Industries and research institutions in pharmaceuticals, geochemistry, nutrition, and materials science rely on its isotopic purity for groundbreaking work.

Application

• Isotope Dilution Mass Spectrometry (IDMS): Serves as a primary spike or tracer for the accurate quantification of natural calcium in clinical, environmental, and food samples.
• Metabolic & Nutritional Research: Used to study calcium absorption, bioavailability, and bone metabolism in biological systems with high precision.
• Geochemical & Environmental Tracer Studies: Acts as a stable isotopic tracer in oceanography, paleoclimatology, and soil science to understand calcium cycling.
• Pharmaceutical Development: Employed in pharmacokinetic studies to trace the fate of calcium-containing drug compounds within the body.
• Certified Reference Material (CRM) Production: A key component in formulating high-accuracy calibration standards and CRMs for analytical laboratories.
• Nuclear Magnetic Resonance (NMR) Studies: Can be used in specialized NMR spectroscopy where the 46Ca isotope provides distinct spectral properties.

Basic Information

Product Name	Calcium46
CAS No.	13981-77-6
Molecular Formula	46Ca
Molecular Weight	45.953689
Synonyms	Calcium-46; 46Ca isotope; Calcium 46; Stable Calcium-46; Calcium, isotope of mass 46; Calcium 46 metal; Calcium-46 element; Ca-46
EINECS	Contact for details

Quality Control

Every batch of Calcium-46 is manufactured and analyzed to meet exacting standards for isotopic and chemical purity. Our quality assurance protocol includes rigorous testing via high-resolution mass spectrometry to confirm isotopic enrichment and trace metal analysis to ensure chemical purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing the isotopic abundance, chemical assay, and results of all specified tests to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, this material should be stored under an inert atmosphere (e.g., argon) in a cool, dry place. For long-term stability, maintain at controlled room temperature (15-25°C) in a desiccated environment. Handle and open containers only in moisture-controlled conditions such as a glove box or dry room to prevent degradation.

Specification

Item	Specification
Appearance	Metal lump, foil, or as specified
Isotopic Enrichment (46Ca)	> 95.0 atom % (Typical 96.0-99.9%)
Chemical Purity (Assay)	> 99.9% (Metals basis)
Identification (MS)	Conforms
Isotopic Distribution (MS)	Reported
Trace Metal Impurities (ICP-MS)	< 1000 ppm total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.