Description

n-(4-Hydroxy-3-(1-Pyrrolidinylmethyl) Phenyl) Acetamide is a specialized organic compound featuring a phenolic acetamide core substituted with a pyrrolidinylmethyl group, offering a unique pharmacophore for advanced chemical synthesis. This compound matters as a critical pharmaceutical intermediate and research chemical for developing novel active molecules, where its structural motif is valued for modulating biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries engaged in innovative drug discovery and custom synthesis programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, analgesics, or other therapeutic areas.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its versatile chemical handle.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents and pesticides.
• Fine Chemical Production: Serves as a precursor for specialized dyes, pigments, or functional materials requiring its specific aromatic amine-phenol structure.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies, given its ability to mimic certain natural substrates.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	n-(4-Hydroxy-3-(1-Pyrrolidinylmethyl) Phenyl) Acetamide
CAS No.	13886-02-7
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	N-[4-Hydroxy-3-(pyrrolidin-1-ylmethyl)phenyl]acetamide; 1-[4-(Acetylamino)-2-hydroxyphenyl]methyl]pyrrolidine; 4'-Hydroxy-3'-(1-pyrrolidinylmethyl)acetanilide; Acetamide, N-[4-hydroxy-3-(1-pyrrolidinylmethyl)phenyl]-; 13886-02-7; N-(4-Hydroxy-3-pyrrolidin-1-ylmethylphenyl)acetamide
EINECS	Contact for details

Quality Control

Our n-(4-Hydroxy-3-(1-Pyrrolidinylmethyl) Phenyl) Acetamide is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.