Description

1-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methoxy]-2-Hexadecanol is a high-value specialty chemical intermediate featuring a unique acetal-protected glycerol ether structure linked to a long-chain fatty alcohol. This compound matters for its role as a versatile synthon in the production of complex lipids, surfactants, and specialty polymers, offering chemists a protected functional handle for selective reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel bioactive compounds and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel lipid-based drug conjugates, prodrugs, and bioactive molecules targeting specific delivery pathways.
• Specialty Surfactant & Emulsifier Precursor: Serves as a key building block for creating non-ionic surfactants with tailored hydrophilic-lipophilic balance (HLB) for cosmetic and agrochemical formulations.
• Advanced Polymer Chemistry: Acts as a monomer or chain extender in the development of functional polyesters, polyethers, and other polymers with modified surface properties.
• Lipid & Membrane Research: Employed in academic and industrial research to construct synthetic lipids and analogs for studying membrane biophysics and developing lipid nanoparticle (LNP) systems.
• Agrochemical Synthesis: Utilized as an intermediate in the production of specialized adjuvants or active ingredients that require specific solubility and penetration characteristics.
• Chemical Biology Probe Development: Provides a scaffold for attaching reporter groups or other functionalities to create tools for studying biological processes.

Basic Information

Item	Detail
Product Name	1-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methoxy]-2-Hexadecanol
CAS No.	13879-81-7
Molecular Formula	C22H44O4
Molecular Weight	372.59 g/mol
Synonyms	2-Hexadecanol, 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]-; 1-O-(2,3-Isopropylidene glyceryl)-2-hexadecanol; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl hexadecyl ether (isomer); Acetal Protected Glyceryl Hexadecyl Ether; Isopropylidene Glyceryl Hexadecyl Ether; Hexadecyl Glyceryl Acetal Ether; Lipid Acetal Intermediate
EINECS	Contact for details

Quality Control

Our 1-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methoxy]-2-Hexadecanol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC or GC), identity (IR, NMR), and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.