Description

1,2-Dihydrocyclobuta[B]Quinoline-8-Carboxylic Acid is a specialized heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, agrochemical discovery, and materials science to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its fused quinoline structure for biological activity.
• Ligand Synthesis: Acts as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: The rigid, conjugated structure makes it a valuable scaffold for developing new organic fluorophores and chemical sensors.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fused-ring chemistry.
• Fine Chemical Production: Integrated into multi-step synthetic routes for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	1,2-Dihydrocyclobuta[B]Quinoline-8-Carboxylic Acid
CAS No.	13848-02-7
Molecular Formula	C₁₂H₉NO₂
Molecular Weight	199.21 g/mol
Synonyms	8-Quinolinecarboxylic acid, 1,2-dihydrocyclobuta[b]quinoline-; Cyclobuta[b]quinoline-8-carboxylic acid, 1,2-dihydro-; 1,2-Dihydrocyclobuta[b]quinoline-8-carboxylic acid; 1,2-Dihydrocyclobuta[b]quinoline-8-carboxylic acid; 13848-02-7 (CAS); 1,2-Dihydrocyclobuta[b]quinoline-8-carboxylate
EINECS	Contact for details

Quality Control

Our 1,2-Dihydrocyclobuta[B]Quinoline-8-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.