Description

(R)-Glycidyltosylate CAS NO 13826-06-5 is a high-value chiral building block and electrophilic epoxide derivative, essential for the stereoselective synthesis of complex organic molecules. Its core value lies in its ability to introduce the (R)-glycidyl moiety into target structures with high enantiomeric purity, enabling the creation of optically active intermediates. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers, antiviral agents, and other active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating chiral polymers and advanced materials with specific optical properties.
• Asymmetric Catalysis Research: A standard substrate for developing and testing new chiral catalysts and methodologies in academic and industrial R&D.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances.
• Proteomics & Bioconjugation: Useful for modifying proteins, peptides, and other biomolecules via reaction with nucleophilic amino acid side chains.

Basic Information

Product Name	(R)-Glycidyltosylate
CAS No.	13826-06-5
Molecular Formula	C10H12O4S
Molecular Weight	228.26 g/mol
Synonyms	(R)-(-)-Glycidyl Tosylate; (R)-Glycidyl 4-Methylbenzenesulfonate; (2R)-(-)-Glycidyl Tosylate; (R)-Oxiran-2-ylmethyl 4-methylbenzenesulfonate; (R)-Epoxypropyl Tosylate; (R)-EPT; (R)-2,3-Epoxypropyl p-Toluenesulfonate; (R)-Glycidyl p-Toluenesulfonate
EINECS	Contact for details

Quality Control

Our (R)-Glycidyltosylate is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity, critical for asymmetric synthesis. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. We adhere to cGMP principles where applicable, and our quality commitment aligns with the standards demanded by pharmaceutical and advanced fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its reactive epoxide functionality, it should be stored separately from strong bases, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.