Description

9-Bromo-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its specific brominated and acetylated structure, which is essential for synthesizing novel corticosteroid analogs and other bioactive molecules. This compound is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on steroid chemistry, drug discovery, and process development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel corticosteroid drugs and anti-inflammatory agents.
• Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) of steroid-based therapeutics.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid manufacturing.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex steroid molecules.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	9-Bromo-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate
CAS No.	13796-49-1
Molecular Formula	C₂₄H₃₁BrO₆
Molecular Weight	495.41 g/mol
Synonyms	9-Bromo-11β,17α,21-Trihydroxy-16α-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate; 9-Bromo-16α-Methylprednisolone 21-Acetate; 9-Bromoprednisolone 21-Acetate; 9-Bromo-δ¹-Cortisol 21-Acetate; 9-Bromo-11β,17,21-Trihydroxy-16α-Methyl-1,4-Pregnadiene-3,20-Dione 21-Acetate; 9-Bromo-16-Methylprednisolone Acetate
EINECS	Contact for details

Quality Control

Our 9-Bromo-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione 21-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.