Description

Ethyl 1,4-Dioxaspiro[4.5]Decane-6-Carboxylate is a versatile spirocyclic ester compound that serves as a crucial synthetic intermediate in advanced organic chemistry. Its unique bicyclic acetal-protected structure makes it a valuable building block for constructing complex molecules with precise stereochemistry. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and fine chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), chiral ligands, and novel fragrance compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Serves as a protected form of a keto-ester, enabling selective reactions in the production of specialty chemicals and advanced materials.
• Fragrance & Flavor Chemistry: Used as a precursor for synthesizing musky, spirocyclic odorants and complex flavoring agents.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides due to its spirocyclic scaffold.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, particularly in asymmetric catalysis and ring-forming reactions.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent for creating polymers with specific architectural features.

Basic Information

Product Name	Ethyl 1,4-Dioxaspiro[4.5]Decane-6-Carboxylate
CAS No.	13747-72-3
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	Ethyl 6-Oxaspiro[4.5]decane-8-carboxylate; 1,4-Dioxaspiro[4.5]decane-6-carboxylic acid ethyl ester; Ethyl 1,4-dioxaspiro[4.5]decane-6-carboxylate; Ethyl 6,9-Dioxaspiro[4.5]decane-8-carboxylate; 6-Carbethoxy-1,4-dioxaspiro[4.5]decane; Acetal-protected ethyl 4-oxocyclohexanecarboxylate; Ethyl 4,4-Ethylenedioxycyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 1,4-Dioxaspiro[4.5]Decane-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.