Description

1-Chloro-4-(Chloromethyl)-2-Methoxybenzene is a versatile chlorinated aromatic building block of significant importance in advanced organic synthesis. This compound matters for its dual reactive sites, the chloromethyl and chloro substituents, which allow for selective functionalization and the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex diaryl ether or benzylamine structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its aromatic chlorine atoms provide sites for further derivatization.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the development of specialty polymers and resins with specific thermal or chemical resistance properties.
• Material Science Research: Utilized in the creation of organic electronic materials, liquid crystals, and other advanced functional materials.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex dyes and organic pigments.

Basic Information

Product Name	1-Chloro-4-(Chloromethyl)-2-Methoxybenzene
CAS No.	13726-18-6
Molecular Formula	C8H8Cl2O
Molecular Weight	191.05 g/mol
Synonyms	2-Chloro-5-(Chloromethyl)anisole; 4-Chloro-3-Methoxybenzyl Chloride; 1-Chloro-4-(Chloromethyl)-2-Methoxybenzene; 2-Methoxy-5-(chloromethyl)chlorobenzene; 3-Methoxy-4-chlorobenzyl chloride; (4-Chloro-3-methoxyphenyl)methyl chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-(Chloromethyl)-2-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.