Description

2-Ethoxy-Triethylphosphonoacetate is a specialized organophosphorus compound, specifically a phosphonoacetate ester, that serves as a versatile building block in advanced organic synthesis. Its primary value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective formation of α,β-unsaturated esters and other complex molecules. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and consistent performance in multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing olefin linkages in drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific alkene geometries.
• Fine Chemical Manufacturing: Employed as a specialized building block for creating complex fragrance compounds, flavors, and functional materials.
• Academic & Industrial R&D: A staple reagent in laboratory-scale research for method development and the synthesis of novel organic compounds for material science.
• Polymer Chemistry: Can be utilized in the synthesis of monomers or functional polymers requiring phosphonate ester groups.

Basic Information

Product Name	2-Ethoxy-Triethylphosphonoacetate
CAS No.	13676-06-7
Molecular Formula	C10H21O5P
Molecular Weight	252.24 g/mol
Synonyms	Triethyl (2-ethoxy-2-oxoethyl)phosphonate; Diethyl (ethoxycarbonylmethyl)phosphonate; (Carbethoxymethyl)phosphonic acid diethyl ester; Diethyl (carbethoxymethyl)phosphonate; Ethyl (diethoxyphosphinyl)acetate; Acetic acid, 2-(diethoxyphosphinyl)-, ethyl ester; 2-(Diethoxyphosphoryl)acetic acid ethyl ester; EINECS 237-173-1
EINECS	237-173-1

Quality Control

Our 2-Ethoxy-Triethylphosphonoacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A detailed Certificate of Analysis (COA) documenting purity, physical properties, and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (g/mL, 20°C)	1.10 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.