Description

4-Chloro-6-Methoxy-Quinoline-3-Carbonitrile is a versatile and high-value heterocyclic building block in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the quinoline scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based drug candidates, including potential kinase inhibitors, antimalarials, and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the biological activity of the quinoline core.
• Material Science Research: Serves as a building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its electron-deficient aromatic system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme functions.
• Academic & Contract Research: Essential for methodological development and novel reaction exploration in academic laboratories and contract research organizations (CROs).
• Fine Chemical Production: Incorporated into the multi-step synthesis of complex fine chemicals and specialty additives.

Basic Information

Product Name	4-Chloro-6-Methoxy-Quinoline-3-Carbonitrile
CAS No.	13669-62-0
Molecular Formula	C₁₁H₇ClN₂O
Molecular Weight	218.64 g/mol
Synonyms	4-Chloro-6-methoxyquinoline-3-carbonitrile; 6-Methoxy-4-chloroquinoline-3-carbonitrile; 3-Cyano-4-chloro-6-methoxyquinoline; 4-Chloro-6-methoxy-3-quinolinecarbonitrile; Quinoline-3-carbonitrile, 4-chloro-6-methoxy-; 13669-62-0 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Methoxy-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.