Description

3-Chloro-2-Oxopropyl Triphenylphosphonium Chloride is a high-value organophosphorus reagent, specifically a functionalized phosphonium salt. This compound matters as a versatile building block in organic synthesis, enabling key transformations like the Wittig reaction to introduce α-chloro ketone functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the preparation of α-chloro ketones and other bioactive molecules via Wittig olefination.
• Agrochemical Active Ingredient Development: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of specialized monomers and polymers with unique properties.
• Academic & Industrial R&D: Serves as a fundamental tool for methodology development and exploring new chemical spaces in organic chemistry.
• Synthesis of Natural Product Analogs: Facilitates the construction of complex, naturally-inspired compounds for biological screening.
• Process Chemistry: Investigated for scalable routes to target molecules in pilot plant and manufacturing settings.

Basic Information

Product Name	3-Chloro-2-Oxopropyl Triphenylphosphonium Chloride
CAS No.	13605-65-7
Molecular Formula	C21H19Cl2OP
Molecular Weight	413.25 g/mol
Synonyms	3-Chloro-2-oxopropyltriphenylphosphonium chloride; (3-Chloro-2-oxopropyl)triphenylphosphonium chloride; 1-Chloro-3-(triphenylphosphonio)acetone chloride; Triphenyl(3-chloro-2-oxopropyl)phosphonium chloride; 3-Chloro-2-oxo-propyltriphenylphosphonium chloride; Acetone, 1-chloro-3-(triphenylphosphonio)-, chloride; Chloroacetone triphenylphosphonium chloride (derivative)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Oxopropyl Triphenylphosphonium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all commercial quantities and are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.