Description

1-(2-Chlorophenyl)-1-Ethanol is a versatile chiral secondary alcohol building block of significant importance in fine chemical synthesis. Its value lies in the combination of a reactive benzylic alcohol group with an ortho-chlorinated aromatic ring, enabling diverse downstream transformations. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a substituted phenethylamine or aryl ethanolamine backbone.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the chlorophenyl moiety provides specific biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as phosphines and oxazolines, crucial for enantioselective synthesis.
• Flavor and Fragrance Industry: Acts as an intermediate for the synthesis of complex aromatic compounds used in specialty perfumery and flavoring agents.
• Material Science Research: Employed in the development of novel monomers for polymers, liquid crystals, and other advanced organic materials with tailored properties.
• Organic Synthesis Building Block: Utilized in a wide range of reactions including esterification, etherification, oxidation to ketones, and nucleophilic substitution of the chlorine atom.

Basic Information

Product Name	1-(2-Chlorophenyl)-1-Ethanol
CAS No.	13524-04-4
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	2-Chloro-α-methylbenzyl alcohol; (2-Chlorophenyl)methylcarbinol; 1-(2-Chlorophenyl)ethanol; α-Methyl-2-chlorobenzyl alcohol; o-Chloro-α-methylbenzyl alcohol; 2-Chloro-1-phenylethanol; 1-(o-Chlorophenyl)ethanol; Benzenemethanol, 2-chloro-α-methyl-
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)-1-Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Purity (GC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.