Description

α-(Diethoxyphosphinyl)Benzeneacrylic Acid Ethyl Ester is a high-purity organophosphorus compound with a versatile α,β-unsaturated ester structure. This chemical serves as a critical intermediate in advanced organic synthesis, enabling the introduction of a phosphonate moiety and an activated alkene in a single molecule. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition or requiring phosphonate bioisosteres.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the phosphonate group enhances systemic activity.
• Horner-Wadsworth-Emmons (HWE) Reaction: Acts as a stabilized phosphonate reagent for the stereoselective synthesis of (E)-alkenes (olefination) in fine chemical manufacturing.
• Material Science Research: Employed in the development of specialty polymers, ligands for metal catalysis, and functionalized organic materials.
• Chemical Biology Probes: Useful for creating activity-based probes or labeled compounds for studying biological pathways.

Basic Information

Product Name	α-(Diethoxyphosphinyl)Benzeneacrylic Acid Ethyl Ester
CAS No.	13507-49-8
Molecular Formula	C15H21O5P
Molecular Weight	312.30 g/mol
Synonyms	Ethyl (α-Diethoxyphosphoryl)cinnamate; Ethyl 2-(Diethoxyphosphoryl)-3-phenylacrylate; Diethyl (1-Ethoxycarbonyl-2-phenylethenyl)phosphonate; (Diethoxyphosphinyl)benzeneacrylic Acid Ethyl Ester; Ethyl α-(Diethoxyphosphinyl)cinnamate; Cinnamic acid, 2-(diethoxyphosphinyl)-, ethyl ester; Phosphonic acid, (1-ethoxycarbonyl-2-phenylethenyl)-, diethyl ester
EINECS	Contact for details

Quality Control

Every batch of α-(Diethoxyphosphinyl)Benzeneacrylic Acid Ethyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and batch-to-batch consistency for your critical synthesis workflows. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.