Description

n-Methyl-o-Toluenesulfonamide is a specialized organic sulfonamide derivative, recognized for its utility as a versatile chemical intermediate and building block in advanced synthesis. Its structure makes it valuable for introducing the N-methyl-o-toluenesulfonyl (Mts) protecting group, which is crucial in multi-step organic and pharmaceutical manufacturing processes. This compound is essential for research laboratories and industrial producers engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where selective protection and deprotection strategies are required.

Application

• As a key protecting group reagent in peptide and oligonucleotide synthesis, particularly for amine functionalities.
• An important chemical intermediate in the multi-step production of pharmaceuticals and agrochemicals.
• Used in organic research for the development of novel sulfonamide-based compounds with potential biological activity.
• Employed in material science for the synthesis of specialty polymers and functional additives.
• Serves as a precursor or building block in fine chemical and custom synthesis projects.
• Potential use in the development of photoacid generators (PAGs) for advanced photoresist formulations in semiconductor manufacturing.

Basic Information

Product Name	n-Methyl-o-Toluenesulfonamide
CAS No.	13440-22-7
Molecular Formula	C8H11NO2S
Molecular Weight	185.24 g/mol
Synonyms	N-Methyl-2-methylbenzenesulfonamide; 2-Methyl-N-methylbenzenesulfonamide; o-Toluenesulfonylmethylamide; Mts-NHMe; N-Methyl-o-toluenesulfonamide; N-Methyl-2-toluenesulfonamide; Methyl(p-tolylsulfonyl)amine (common misnomer for ortho isomer); Benzenesulfonamide, N-methyl-2-methyl-
EINECS	Contact for details

Quality Control

Our n-Methyl-o-Toluenesulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.