Description

2-Ethoxytetrahydrofuran is a versatile heterocyclic ether and a valuable chemical intermediate. This compound is particularly significant for its role as a protected form of 4-hydroxybutyraldehyde, enabling controlled synthetic pathways in complex organic synthesis. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in research, process development, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and other heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its ether functionality is leveraged for structural modifications.
• Fine Chemical Manufacturing: Serves as a precursor and solvent in the synthesis of flavors, fragrances, and other high-value specialty chemicals.
• Polymer Chemistry: Acts as a monomer or modifying agent in the development of specialized polymers and resins.
• Laboratory Research: Employed as a reagent in academic and industrial R&D for exploring new synthetic methodologies and protecting group strategies.
• Chemical Derivatization: Useful for introducing the ethoxytetrahydrofuran moiety into larger molecular frameworks to alter solubility or reactivity.

Basic Information

Product Name	2-Ethoxytetrahydrofuran
CAS No.	13436-46-9
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	2-Ethoxyoxolane; 2-Ethoxytetrahydrofuran; Tetrahydro-2-ethoxyfuran; 2-Ethoxy-tetrahydro-furan; Ethyl tetrahydro-2-furyl ether; 2-Ethoxyoxacyclopentane
EINECS	236-577-8

Quality Control

Our 2-Ethoxytetrahydrofuran is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC, identity confirmation (IR), and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain product integrity. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.410 - 1.415
Density (20°C)	0.92 - 0.96 g/mL
Boiling Point	Approx. 130 - 135 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.