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(1S)-(-)-Camphanic Acid CAS NO 13429-83-9


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CAS No.:13429-83-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1S)-(-)-Camphanic Acid is a high-purity, enantiomerically pure derivative of camphor, widely recognized as a versatile chiral auxiliary and resolving agent in asymmetric synthesis. Its rigid, bulky structure is critical for inducing stereoselectivity in chemical reactions, enabling the production of single-enantiomer compounds. This product is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and fine chemical industries, where precise chiral control is paramount.

Application

  • Chiral Resolution Agent: For the separation of racemic mixtures of alcohols, amines, and other chiral compounds via diastereomeric salt formation.
  • Asymmetric Synthesis: Acts as a key chiral auxiliary in the synthesis of enantiomerically pure pharmaceuticals, natural products, and catalysts.
  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
  • Analytical Chemistry: Employed as a derivatizing agent for chiral analysis by HPLC, GC, or NMR to determine enantiomeric excess (ee).
  • Agrochemical Synthesis: Facilitates the production of chiral pesticides and herbicides with enhanced biological activity and environmental profile.
  • Material Science Research: Serves as a building block for chiral ligands and organocatalysts used in polymer and advanced material synthesis.

Basic Information

Product Name (1S)-(-)-Camphanic Acid
CAS No. 13429-83-9
Molecular Formula C10H14O4
Molecular Weight 198.22 g/mol
Synonyms (-)-Camphanic Acid; (1S)-Camphanic Acid; L-(-)-Camphanic Acid; (1S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride; 3-Oxatricyclo[3.2.1.02,4]octane-6-carboxylic acid, 4,7,7-trimethyl-, (1S)-; Camphan-1-acid; (1S)-(-)-Camphanic acid; Camphanic Acid (-)-
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Quality Control

Our (1S)-(-)-Camphanic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) verification, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing purity, specific rotation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Specific Rotation [α]D20 -19.0° to -21.0° (c=1 in CHCl3)
Melting Point 198°C - 202°C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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