Description

4,6-o-Ethylidene-D-Glucopyranose is a specialized carbohydrate derivative, serving as a crucial chiral building block and protective group intermediate in advanced organic synthesis. Its value lies in its ability to impart stereochemical control and modify solubility profiles in complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other complex bioactive molecules.
• Glycochemistry & Glycobiology: Used in the preparation of glycosyl donors and acceptors for oligosaccharide and glycoconjugate synthesis.
• Protective Group Chemistry: The ethylidene acetal group serves as a temporary protecting group for diols in multi-step synthetic sequences.
• Catalyst & Ligand Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Research: Utilized in developing novel, stereospecific pesticides and plant growth regulators.

Basic Information

Product Name	4,6-o-Ethylidene-D-Glucopyranose
CAS No.	13403-24-2
Molecular Formula	C8H14O6
Molecular Weight	206.19 g/mol
Synonyms	1,2-O-Isopropylidene-α-D-glucofuranose 5,6-acetonide; D-Glucose, 4,6-O-ethylidene-; 4,6-O-Ethylidene-D-glucose; Ethylidene-D-glucose; α-D-Glucopyranose, 4,6-O-ethylidene-; 4,6-Ethylidene-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 4,6-o-Ethylidene-D-Glucopyranose is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.