Description

8-Hydroxybenzo[A]Pyrene is a hydroxylated derivative of the polycyclic aromatic hydrocarbon benzo[a]pyrene, a compound of significant research interest. This specific derivative is primarily utilized as a critical analytical standard and research chemical in environmental and toxicological studies. It is essential for scientists and laboratories focused on metabolite identification, biomarker research, and the study of polycyclic aromatic hydrocarbon (PAH) transformation pathways.

Application

• Analytical Reference Standard: Used for the calibration and validation of analytical instruments (HPLC, GC-MS, LC-MS) in environmental and food safety testing.
• Metabolite Research: Serves as a key compound in studying the metabolic activation and detoxification pathways of benzo[a]pyrene in biological systems.
• Environmental Monitoring: Employed as a standard for the quantification of hydroxylated PAH metabolites in soil, water, and air particulate matter samples.
• Biomarker Development: Used in research to develop and validate biomarkers of exposure to carcinogenic PAHs for occupational and public health studies.
• Toxicological Studies: Applied in *in vitro* and *in vivo* research to investigate the comparative toxicity and mutagenicity of different PAH metabolites.
• Pharmaceutical Research: Potential use in studies exploring enzyme inhibition related to PAH metabolism, such as cytochrome P450 interactions.

Basic Information

Product Name	8-Hydroxybenzo[A]Pyrene
CAS No.	13345-26-1
Molecular Formula	C₂₀H₁₂O
Molecular Weight	268.31 g/mol
Synonyms	8-Hydroxybenzo[a]pyrene; 8-Hydroxy-BaP; 8-OH-BaP; Benzo[a]pyren-8-ol; 8-HBP; Hydroxybenzo(a)pyrene; 1-Hydroxybenzo[a]pyrene (positional isomer); PAH Metabolite Standard
EINECS	Contact for details

Quality Control

Our high-purity 8-Hydroxybenzo[A]Pyrene is manufactured and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We ensure compliance with relevant standards for research chemicals, providing the traceability and data integrity required for analytical and toxicological work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in secondary packaging or amber glass to minimize exposure during storage.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, methanol, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.