Description

3-Hydroxybenzo[A]Pyrene is a hydroxylated derivative of the well-studied polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene. This compound is of significant interest as a key metabolite and biomarker for exposure to its parent carcinogen, making it a critical reference standard for analytical and toxicological research. It is primarily utilized by environmental testing laboratories, academic research institutions, and pharmaceutical companies engaged in metabolic and carcinogenicity studies. Our supply ensures high-purity material essential for generating reliable and reproducible scientific data.

Application

• Analytical Reference Standard: Used as a certified standard for the precise quantification of benzo[a]pyrene metabolites in complex matrices via HPLC, GC-MS, or LC-MS.
• Toxicology & Metabolic Studies: Serves as a critical reagent in research investigating the metabolic activation pathways, DNA adduct formation, and carcinogenic mechanisms of PAHs.
• Environmental Monitoring: Employed in method development and calibration for detecting and monitoring human and ecological exposure to airborne particulates, soil, and water contaminants.
• Biomarker Research: Essential for developing and validating assays to measure 3-hydroxybenzo[a]pyrene as a biomarker of recent exposure to benzo[a]pyrene in occupational health and epidemiological studies.
• Pharmaceutical Research: Used in studies focusing on chemoprevention and the efficacy of compounds designed to inhibit the bioactivation of procarcinogens.
• Quality Control & Assurance: Provides a benchmark for internal quality control procedures in laboratories performing PAH and metabolite analysis.

Basic Information

Product Name	3-Hydroxybenzo[A]Pyrene
CAS No.	13345-21-6
Molecular Formula	C₂₀H₁₂O
Molecular Weight	268.31 g/mol
Synonyms	3-Hydroxybenzo[a]pyrene; 3-OH-BaP; Benzo[a]pyren-3-ol; 3-Hydroxy-BAP; 3-HBP; 3-Hydroxybenzopyrene; 3-Hydroxy-B(a)P; 3-HO-BaP
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxybenzo[A]Pyrene is produced and handled under strict quality management protocols. We provide comprehensive analytical documentation to support research integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.