Description

1,5-Dichloro-2-Methoxy-3-Methylbenzene is a versatile halogenated aromatic compound that serves as a critical intermediate in advanced organic synthesis. Its unique substitution pattern makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring a specific chlorinated anisole backbone.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its dichloro-methoxy structure imparts desired biological activity.
• Material Science: Serves as a precursor for liquid crystals, organic semiconductors, and advanced polymers, leveraging its aromaticity and substituents for tuning material properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution to introduce functionalized aryl groups into target molecules.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and pigments, where the methyl and methoxy groups can modify color and stability.
• Research & Development: Essential for medicinal chemistry and process chemistry research in both academic and industrial laboratories for exploring new chemical entities.

Basic Information

Product Name	1,5-Dichloro-2-Methoxy-3-Methylbenzene
CAS No.	13334-73-1
Molecular Formula	C8H8Cl2O
Molecular Weight	191.05 g/mol
Synonyms	2,4-Dichloro-6-methoxy-3-methylbenzene; 3-Methyl-2,4-dichloroanisole; 1,5-Dichloro-2-methoxy-3-methyl-benzene; 2-Methoxy-3-methyl-1,5-dichlorobenzene; 3-Methyl-2,4-dichloro-1-methoxybenzene; Benzene, 1,5-dichloro-2-methoxy-3-methyl-
EINECS	Contact for details

Quality Control

Our 1,5-Dichloro-2-Methoxy-3-Methylbenzene is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.