Description

Methyl 2-(3-Chlorophenyl)-2-Hydroxyacetate is a versatile chiral building block and synthetic intermediate of significant importance in fine chemical synthesis. Its value lies in the presence of both a reactive ester group and a benzylic hydroxyl group on a chlorinated aromatic scaffold, enabling diverse chemical transformations. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drugs, particularly those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators that require specific chlorophenyl motifs.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, crucial for producing enantiomerically pure compounds.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and advanced materials requiring precise molecular architecture.
• Academic and R&D: Serves as a standard or starting material in organic chemistry research for method development and novel compound libraries.

Basic Information

Product Name	Methyl 2-(3-Chlorophenyl)-2-Hydroxyacetate
CAS No.	13305-18-5
Molecular Formula	C9H9ClO3
Molecular Weight	200.62 g/mol
Synonyms	Methyl (3-chlorophenyl)(hydroxy)acetate; 2-Hydroxy-2-(3-chlorophenyl)acetic acid methyl ester; Methyl 2-hydroxy-2-(3-chlorophenyl)acetate; 3-Chloromandelic acid methyl ester; Methyl 3-chloromandelate; α-Hydroxy-3-chlorobenzeneacetic acid methyl ester; (3-Chlorophenyl)(hydroxy)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(3-Chlorophenyl)-2-Hydroxyacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.