Description

4-Chloro-2-Butyn-1-Ol is a versatile halogenated alkyne alcohol, a key building block in advanced organic synthesis. Its unique structure, featuring both a chloro and a hydroxyl group on an acetylene backbone, makes it a valuable intermediate for constructing complex molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring acetylene or propargylic ether/ester motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its reactive sites allow for the introduction of specific biological activity.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties, such as adhesives, coatings, and conductive materials.
• Organic Synthesis Building Block: Employed in click chemistry (e.g., CuAAC reactions), Sonogashira couplings, and other catalytic transformations to introduce functionalized acetylene units.
• Liquid Crystal & Electronic Chemical Intermediate: Utilized in the synthesis of advanced organic electronic materials and liquid crystal compounds.

Basic Information

Product Name	4-Chloro-2-Butyn-1-Ol
CAS No.	13280-07-4
Molecular Formula	C4H5ClO
Molecular Weight	104.54 g/mol
Synonyms	4-Chloro-2-butyn-1-ol; 4-Chlorobut-2-yn-1-ol; 1-Chloro-3-butyn-2-ol; 2-Butyn-1-ol, 4-chloro-; 4-Chloro-2-butynol; 4-Chloro-but-2-in-1-ol; 4-Chloro-but-2-yn-1-ol; 4-Chloro-2-butyn-1-ol (stabilized with TBC)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Butyn-1-Ol is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopy (IR, NMR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. Due to its reactive functional groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.