Description

(R)-2-(2,2-Diethoxyethyl)Oxirane is a chiral epoxide derivative of significant value as a versatile synthetic building block in fine chemical and pharmaceutical synthesis. Its unique structure, featuring both an epoxide ring and a protected aldehyde equivalent, makes it a critical precursor for constructing complex, optically active molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure compounds for advanced applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, cardiovascular, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Building Block: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring precise stereocontrol.
• Polymer Modification: Can be used to introduce chiral centers or reactive epoxide functionalities into polymer chains for specialty materials.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-2-(2,2-Diethoxyethyl)Oxirane
CAS No.	13269-78-8
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(R)-Glycidyl Acetaldehyde Diethyl Acetal; (R)-2,2-Diethoxyethyloxirane; (R)-3,3-Diethoxy-1,2-epoxypropane; (2R)-2-[(2,2-Diethoxyethyl)oxirane]; (R)-(-)-2-(2,2-Diethoxyethyl)oxirane; (R)-Epichlorohydrin Diethyl Acetal (related precursor); (R)-1,2-Epoxy-3,3-diethoxypropane; (R)-Oxiran-2-ylmethanediyl diethyl ether
EINECS	Contact for details

Quality Control

Our (R)-2-(2,2-Diethoxyethyl)Oxirane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), enantiomeric excess (ee), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.