Description

Z-Ile-Phe-Oh is a protected dipeptide derivative, specifically the Z-protected form of Isoleucine-Phenylalanine. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, bioactive compounds, and complex organic molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled, sequential addition of amino acids.
• Pharmaceutical Research: Synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Production of custom peptides for structure-activity relationship (SAR) studies and enzyme substrate investigations.
• Organic Synthesis: A versatile chiral synthon for constructing more complex molecular architectures.
• Protecting Group Chemistry: Demonstrates the application of the carboxybenzyl (Z) group for amine protection in multi-step syntheses.

Basic Information

Item	Detail
Product Name	Z-Ile-Phe-Oh
CAS No.	13254-07-4
Molecular Formula	C26H34N2O5
Molecular Weight	454.56 g/mol
Synonyms	N-Carbobenzyloxy-L-isoleucyl-L-phenylalanine; Z-L-Ile-L-Phe-OH; Cbz-Ile-Phe-OH; Nα-Cbz-L-isoleucyl-L-phenylalanine; Benzyloxycarbonyl-L-isoleucyl-L-phenylalanine; (2S)-2-[[(2S)-2-[[(phenylmethoxy)carbonyl]amino]-3-methylpentanoyl]amino]-3-phenylpropanoic acid; Z-Ile-Phe; CBZ-Isoleucine-Phenylalanine
EINECS	Contact for details

Quality Control

Our Z-Ile-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.