Description

2-Chloro-N-(1-Phenylethyl)Acetamide is a specialized organic intermediate featuring a chloroacetamide group linked to a chiral phenylethyl moiety. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and fine chemical synthesis, where it is valued for introducing specific functional groups and chiral centers into target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other performance chemicals requiring specific amide functionalities.
• Organic Synthesis Research: A valuable reagent in academic and industrial laboratories for studying nucleophilic substitution reactions and amide bond formation.
• Ligand and Catalyst Development: Potential use in creating chiral ligands for asymmetric catalysis due to its inherent stereocenter.

Basic Information

Product Name	2-Chloro-N-(1-Phenylethyl)Acetamide
CAS No.	13230-80-3
Molecular Formula	C10H12ClNO
Molecular Weight	197.66 g/mol
Synonyms	N-(1-Phenylethyl)-2-chloroacetamide; 2-Chloro-N-(α-methylbenzyl)acetamide; α-Chloro-N-(1-phenylethyl)acetamide; Acetamide, 2-chloro-N-(1-phenylethyl)-; 2-Chloro-N-(1-phenylethyl)ethanamide; N-(α-Methylbenzyl)chloroacetamide; 1-Phenylethylaminochloroacetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(1-Phenylethyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), chiral purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (for specified enantiomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.