Description

Methyl-4,6-o-Ethylidene-α-D-Glucopyranoside CAS NO 13225-11-1 is a protected carbohydrate derivative, specifically a methyl glucoside with an ethylidene acetal protecting group at the 4 and 6 hydroxyl positions. This compound is a crucial chiral building block and intermediate in sophisticated organic synthesis, offering a rigid, defined stereochemistry for constructing complex molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the synthesis of complex drug candidates, nucleoside analogs, and glycosidase inhibitors.
• Agrochemical Research: Used in the development of novel, biologically active compounds such as herbicides, fungicides, and plant growth regulators.
• Glycochemistry & Glycobiology: Acts as a fundamental starting material for the preparation of more complex oligosaccharides, glycoconjugates, and glycomimetics.
• Fine Chemical Synthesis: Employed as a versatile intermediate in the production of specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: Essential for methodological development in organic synthesis, catalysis research, and exploring new chemical spaces.
• Protecting Group Strategy: The ethylidene group provides a robust protective mask for diols, which can be selectively manipulated or removed under controlled conditions.

Basic Information

Product Name	Methyl-4,6-o-Ethylidene-α-D-Glucopyranoside
CAS No.	13225-11-1
Molecular Formula	C9H16O6
Molecular Weight	220.22 g/mol
Synonyms	Methyl 4,6-O-Ethylidene-α-D-glucopyranoside; α-Methyl 4,6-O-ethylidene-D-glucopyranoside; 1-O-Methyl-4,6-O-ethylidene-α-D-glucopyranose; Methyl α-D-glucopyranoside 4,6-ethylidene acetal; 4,6-O-Ethylidene-α-methyl-D-glucoside; (4R,5S,6R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-methoxy-4,5-O-ethylideneoxane
EINECS	Contact for details

Quality Control

Our Methyl-4,6-o-Ethylidene-α-D-Glucopyranoside is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.