Description

1,4-Dimethoxy-2,3,5,6-Tetramethylbenzene is a high-purity, multi-substituted benzene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block and ligand precursor for the development of complex chemical architectures. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of complex drug molecules, particularly those requiring sterically hindered, electron-rich aromatic systems.
• Ligand Synthesis: Serves as a precursor for the development of specialized ligands used in catalysis, such as phosphines or N-heterocyclic carbenes (NHCs), for transition metal-catalyzed cross-coupling reactions.
• Organic Electronic Materials: Used in the research and development of organic semiconductors, charge-transport materials, and photoactive compounds due to its stable, substituted aromatic core.
• Agrochemical Research: Employed as a building block for novel active ingredients, including herbicides and fungicides, where its specific substitution pattern can influence biological activity.
• Dye and Pigment Chemistry: Acts as an intermediate in the synthesis of specialized dyes and pigments, where the dimethoxy and tetramethyl groups modify color and stability properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on electrophilic aromatic substitution and directed metalation.

Basic Information

Product Name	1,4-Dimethoxy-2,3,5,6-Tetramethylbenzene
CAS No.	13199-54-7
Molecular Formula	C12H18O2
Molecular Weight	194.27 g/mol
Synonyms	Durene, 1,4-Dimethoxy-2,3,5,6-tetramethyl-; 2,3,5,6-Tetramethyl-1,4-dimethoxybenzene; 1,4-Dimethoxydurene; Benzene, 1,4-dimethoxy-2,3,5,6-tetramethyl-; NSC 403119; Durene dimethylether
EINECS	Contact for details

Quality Control

Our 1,4-Dimethoxy-2,3,5,6-Tetramethylbenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.