Description

α-D-Glucuronic Acid-1-Phosphate is a key phosphorylated sugar acid derivative, serving as a crucial biosynthetic intermediate in metabolic pathways. Its primary commercial value lies in its role as a precursor for the synthesis of UDP-glucuronic acid, a vital substrate for glucuronidation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, biochemical, and life science industries, particularly for drug metabolism studies, enzyme research, and the production of specialized biochemical reagents.

Application

• Biochemical Research & Enzyme Studies: Critical substrate for studying glycosyltransferases, sulfotransferases, and other enzymes involved in carbohydrate metabolism and detoxification pathways.
• Pharmaceutical Intermediate: Acts as a key precursor in the synthesis of UDP-glucuronic acid, used in research for drug conjugation and metabolism (glucuronidation) studies.
• Diagnostic Reagent Manufacturing: Used in the formulation of diagnostic kits and assays that measure enzyme activity or metabolic pathway functions.
• Glycobiology & Glycoconjugate Synthesis: Serves as a building block for the chemical and enzymatic synthesis of complex oligosaccharides, proteoglycans, and other glycoconjugates.
• Metabolite Standard: Employed as a high-purity analytical standard in LC-MS, HPLC, and other chromatographic techniques for quantitative analysis in biological samples.
• Nutritional & Cosmetic Science: Investigated for its role in hyaluronic acid biosynthesis, relevant for advanced skincare and nutraceutical research.

Basic Information

Product Name	α-D-Glucuronic Acid-1-Phosphate
CAS No.	13168-11-1
Molecular Formula	C6H11O10P
Molecular Weight	274.12 g/mol
Synonyms	D-Glucuronic Acid 1-Phosphate; α-D-Glucopyranuronic Acid 1-Phosphate; Glucuronic Acid-1-P; 1-O-Phosphono-α-D-glucopyranuronic Acid; (2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(phosphonooxy)methyl]oxane-2-carboxylic Acid; α-D-Glucuronate 1-phosphate; GlcA-1-P
EINECS	Contact for details

Quality Control

Our α-D-Glucuronic Acid-1-Phosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for moisture and residual solvents, to ensure it meets the exacting standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.