Description

Dibenz(A,J)Anthracene trans-3,4-Diol-Syn-1,2-Epoxide is a high-purity, synthetically derived polycyclic aromatic hydrocarbon (PAH) metabolite. This compound is of significant interest in toxicological and carcinogenicity research, serving as a critical reference standard and active metabolite for mechanistic studies. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and environmental testing facilities investigating the metabolic activation pathways and DNA adduct formation of complex hydrocarbons.

Application

• Biochemical Research: Used as a reference standard in studies of polycyclic aromatic hydrocarbon (PAH) metabolism and activation pathways.
• Toxicology & Carcinogenicity Studies: Serves as a key metabolite for investigating the mechanisms of DNA damage and mutagenesis induced by dibenzanthracenes.
• Analytical Method Development: Employed as a certified reference material (CRM) for calibrating analytical instruments like HPLC, GC-MS, and LC-MS in environmental and biological monitoring.
• Pharmaceutical R&D: Used in early-stage discovery to understand the bioactivation of potential drug candidates or environmental toxins.
• Academic Research: A vital tool for universities and research institutes focusing on chemical carcinogenesis and molecular toxicology.
• Quality Control: Acts as a purity standard for laboratories synthesizing or analyzing related PAH metabolites.

Basic Information

Item	Detail
Product Name	Dibenz(A,J)Anthracene trans-3,4-Diol-Syn-1,2-Epoxide
CAS No.	13148-65-7
Molecular Formula	C22H14O3
Molecular Weight	326.35 g/mol
Synonyms	Dibenz[a,j]anthracene 3,4-diol 1,2-epoxide; anti-DB[a,j]A-3,4-diol-1,2-epoxide; DB[a,j]A DE-2; Dibenz(a,j)anthracene-3,4-dihydrodiol-1,2-epoxide; (+/-)-anti-3,4-Dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene; 1,2-Epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene; PAH Metabolite (DB[a,j]A)
EINECS	Contact for details

Quality Control

Every batch of Dibenz(A,J)Anthracene trans-3,4-Diol-Syn-1,2-Epoxide is produced and analyzed under strict quality protocols to ensure identity, purity, and stability. Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Comprehensive analytical data, including HPLC purity and spectroscopic confirmation, is documented. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, store desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF; sparingly soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.