Description

(S)-(+)-2-Hydroxy-2-Phenylpropionic Acid is a high-purity chiral building block and resolving agent of significant importance in asymmetric synthesis. Its enantiomeric purity makes it a critical component for the production of optically active pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Chiral Resolution Agent: Used for the separation of racemic mixtures of amines and other basic compounds.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly non-steroidal anti-inflammatory drugs (NSAIDs).
• Asymmetric Synthesis Catalyst: Employed as a ligand or precursor in metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Industry: Serves as an intermediate for the synthesis of specific chiral aroma compounds.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	(S)-(+)-2-Hydroxy-2-Phenylpropionic Acid
CAS No.	13113-71-8
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	(S)-(+)-2-Phenyl-2-hydroxypropionic Acid; (S)-2-Hydroxy-2-phenylpropanoic Acid; (S)-2-Phenyl-2-hydroxypropanoic Acid; (S)-2-Phenyl-2-lactic Acid; (S)-Atrolactic Acid; (S)-α-Hydroxy-α-methylbenzenacetic Acid; (S)-α-Methylmandelic Acid; (S)-Oxyatropic Acid
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Hydroxy-2-Phenylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	118°C - 122°C
Specific Rotation [α]D20	+80° to +85° (c=1 in methanol)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.