Description

α,β-1-Methyl-D-Ribofuranoside is a key carbohydrate derivative and protected ribose analog. This compound is valued for its role as a versatile chiral building block and synthetic intermediate in advanced organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical and nucleoside chemistry sectors for developing novel therapeutics and fine chemicals.

Application

• Nucleoside and Nucleotide Synthesis: Serves as a crucial protected intermediate in the synthesis of modified nucleosides, nucleotides, and their analogs for antiviral and anticancer research.
• Pharmaceutical Intermediates: Used as a chiral precursor in the production of complex active pharmaceutical ingredients (APIs) and prodrugs.
• Glycochemistry Research: Acts as a building block for constructing oligosaccharides, glycoconjugates, and other biologically active carbohydrate derivatives.
• Biochemical Tool Development: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and molecular probes for biological studies.
• Fine Chemical Production: Utilized in the scalable synthesis of specialty chemicals requiring high-purity chiral components.

Basic Information

Product Name	α,β-1-Methyl-D-Ribofuranoside
CAS No.	13039-63-9
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	1-Methyl-D-ribofuranoside (α,β-mixture); Methyl D-ribofuranoside; D-Ribose, methyl glycoside; Methyl riboside; 1-O-Methyl-D-ribofuranose; NSC 403697; Methyl α/β-D-ribofuranoside
EINECS	235-904-8

Quality Control

Our α,β-1-Methyl-D-Ribofuranoside is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications, including assay by HPLC, optical rotation, and residual solvent analysis. Our quality commitment supports applications in GMP-aligned research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (α/β mixture)
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.