Description

trans-4-tert-Butylcyclohexylmethanol is a high-purity, stereochemically defined cyclohexane derivative valued for its role as a versatile chiral intermediate and building block in advanced organic synthesis. Its rigid, bulky structure makes it particularly significant for imparting specific steric and electronic properties to target molecules. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty fragrance industries seeking to develop novel active ingredients and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in steroidal and hormone-related therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its structural motif can influence biological activity and selectivity.
• Liquid Crystal Materials: Serves as a precursor or a modifying agent in the production of liquid crystal displays (LCDs) due to its stable cyclohexyl core.
• Fragrance & Flavor Chemistry: Acts as an intermediate for synthesizing musky, woody, or amber fragrance compounds with enhanced stability.
• Polymer Additives: Utilized as a monomer or modifier to create polymers with specific thermal and mechanical properties.
• Organic Synthesis Reagent: Employed in asymmetric synthesis and catalysis as a chiral auxiliary or ligand precursor.

Basic Information

Product Name	trans-4-tert-Butylcyclohexylmethanol
CAS No.	13004-06-3
Molecular Formula	C11H22O
Molecular Weight	170.29 g/mol
Synonyms	(trans-4-tert-Butylcyclohexyl)methanol; 4-tert-Butylcyclohexanemethanol, trans-; trans-4-(1,1-Dimethylethyl)cyclohexanemethanol; (1r,4r)-4-(tert-Butyl)cyclohexylmethanol; NSC 403697; trans-p-tert-Butylcyclohexylmethanol; 4-tert-Butyl-1-cyclohexylmethanol (trans)
EINECS	235-857-9

Quality Control

Our trans-4-tert-Butylcyclohexylmethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by GC/HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Chiral Purity (trans-isomer)	≥ 99.0%
Melting Point	70 - 74 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.